Advanced KD-Pür® Technology

From very early on, KD Pharma Group’s manufacturing practices were specifically designed to meet stringent Active Pharmaceutical Ingredient (API) standards. It is this commitment to exceptionally high standards that has made KD Pharma the leading producer of highly purified API Omega-3 fatty acids. These stringent standards carry over to all the oils we produce.

Our KD-Pür® technology gently extracts and purifies Omega-3’s in a pharmaceutical GMP certified facility. This advanced technology is capable of purifying highly sensitive Omega-3’s without the use of excessive heat, chemical solvents (green technology) or oxygen.

KD Pharma Group has a unique toolbox of technologies to create every possible concentrate from natural oils.

Main technology groups are:

  • KD-Pür® supercritical extraction technology
  • KD-Pür® -enhanced silver and supercritical extraction technology
  • KD-Pür® simulated moving bed technology

KD-Pür® Supercritical fluid technology

The KD-Pür® Technology is a combination of Supercritical Fluid Extraction (SFE) and Supercritical Fluid Chromatography (SFC). This unique combination process delivers a superior quality of Omega-3 concentrates.

The process starts with SFE, which involves using supercritical carbon dioxide (sCO2) to gently extract ethyl esters from unwanted elements such as glycerides, free fatty acids, dyes, pollutants and cholesterol.

During SFE, Omega-3’s are not exposed to excessive heating and never come in contact with oxygen. It is well known that high temperature impacts Omega3 quality and the elimination of oxygen, protects Omega-3 from oxidation as well as from organisms that would otherwise thrive in an oxygen environment. An additional benefit of CO2 is that heavy metals and other impurities are insoluble in it, which allows for an extremely high level of purity to be achieved without the use of chemicals.

In the SFC process, the oil coming from the SFE process is passed through a chromatographic column which is packed with a highly selective separation material. While passing through this column, the fatty acids get separated according to their size and degree of unsaturation. This allows the individual fractions enriched for specific Omega 3’s to leave the column at separated intervals. Finally the CO2 is released, allowing for an exceptionally high level of purity for the Omega-3 concentrates.

Unlike some other extraction methods, with KD-Pür® technology, no chemical solvents, water, sugar, saturated fatty acids, cholesterol or proteins can be found in the finished oil. 

KD Pür-enhanced technology

KD Pür-enhanced technology is a further development of the KD-Pür® technology, where ultra-high concentrations of EPA; DHA, DPA and other specific Omega-3 Components can be achieved

This technology uses the supercritical process steps and also includes a silver-based extraction steps.

With this technology, natural oils can be extracted to previously unheard-of levels of purity. Ultra-high levels of Omega-3 such as EPA, DHA, DPA, Omega-6, Omega-7, Omega-9 are made into very pure concentrates.

Impurities are minimized to extremely low levels.

KD-Pür® simulated moving bed technology

The simulated moving bed (SMB) process is a highly engineered process for implementing chromatographic separation. It is used to separate one chemical compound or one class of chemical compounds from one or more other chemical compounds based on their geometry and has advantages over using simple (batch) HPLC chromatography.

The technology allows the production of large quantities of highly purified material at a continuous and high rate of production, and decreases solvent and energy requirements.

When combined with other KD Pharma technologies, SMB can produce extremely high concentrates of EPA, DHA, DPA and other specific Omega-3s.